The aim of the present study is to investigate the antiradical activities of various solvent extracts of the aerial part of e. Deadly diseases of this century were mainly caused by bacterial and fungal infections. There are several published reports describing the antimicrobial activity of various crude plant extracts 2,3. The in vivo antimalarial activity of the euphorbia hirta extract doses 200, 400 and 800 mgkg body weight against p. Crude extracts were prepared from aerial parts of euphorbia hirta linn. Antibacterial activity of crude extracts of euphorbia hirta against. Pdf antibacterial activity of euphorbia hirta extracts. Note the purpleblotched leaves, a unique feature of. Asian pacific journal of tropical medicine 20186390 390 assay. Antimicrobial activity of caesalpinia pulcherrima, euphorbia. Article pdf available in world journal of pharmaceutical research august 2017 with 370 reads how we measure reads. The present study is carried out by evaluation of euphorbia hirta and calotropisprocera against mdr cultures. Our results showed that the ethanolic, extract of e.
Preliminary phytochemical investigation of extract of leaves. The hydroxyl radical scavenging activity of euphorbia hirta extract was assayed by following the 2deoxyribose oxidation method. Herbal medicine has been used in many parts of the world. Itis taxonomy is based on the latest scientific consensus available, and is provided as a general reference source for interested parties. Phytochemical, antimicrobial activity, euphorbia hirta. Antioxidant activity of ethanolic and aqueous extracts of whole plant of euphorbia hirta materials and methods plant material euphorbia hirta the whole plant was collected, from in and around palakkad, kerala, india and identified and authenticated by dr. Preliminery screening for antiinflammatory activity using 5lipoxygenase assay has been carried out on 31 species of plant. Euphorbia hirta was found to be immunostimulatory at concentrations ranging from 0. Stems are rounded, solid and hairy with abundant milksap. Antidiabetic and free radicals scavenging potential of. Pharmacology and therapeutic potential of euphorbia hirta.
Antimicrobial activity and cytotoxicity evaluation of euphorbia hirta. Antiasthmatic activity ethanolic extract of euphorbia hirta was evaluated using in vitro goat tracheal chain preparation model and clonidine induced catalepsy in mice model. While every effort has been made to provide the most reliable and uptodate information available, ultimate legal requirements with respect to species are contained in. Antimicrobial activity and cytotoxicity evaluation of. It demonstrated activity in experimental models of diarrhoea induced by castor oil, arachidonic acid and prostaglandin e. It was the mainstay of many early civilizations and still the most widely practiced form of medicine in the world today. Pdf antimicrobial activity of fresh latex, juice and. Euphorbia hirta, a pantropic herb has been reported to be pharmacologically active. Antimicrobial activity of flavonoids free and bound of euphorbia hirta l. Phytochemical screening and antimicrobial study euphorbia. However, further investigation with ethnopharmacological approach is needed for better understanding of its utility in health care.
In west africa the plant is also known for its effect in stimulating the production of mothers milk. Review of the phytochemical and pharmacological activities of euphorbia hirta linn. Assessment of immunomodulatory activity of euphorbia hirta l. Antibacterial activities and phytochemical screening of the. The agar diffusion method was used to determine the antibacterial activity on staphylococcus aureus, e coli, pseudomonas aeruginosa. This study reports one another not widely reported property of the plant, immunomodulatory activity, which has been proved using simple techniques like the macrophage activity testing, carbon clearance test and mast cell degranulation assay.
Insomnia, phenoborbitone, euphorbia hirta, sedative. Euphorbia hirta, phytochemical, methanolic extract, hexane extract, aqueous extract, enteric infections, antimicrobial activity. However, it is not a legal authority for statutory or regulatory purposes. Biologically important plants were discovered by evaluation of ethno pharmacological data and they are locally populated with immediate therapeutic action. In asia the asthma weed is mainly used for asthma and diseases of the respiratory tract. P jayraman, director of plant anatomy research centre, and chennai. Leaves are opposite, elliptic oblong to oblong lanceolate, acute or subacute, dark green above, pale beneath, 1 3 cm long, blotched with purple in the middle, and toothed at. Dengueaid is a potent herbal supplement which utilizes the extracts from euphorbia hirta linn herbs which is widely known as tawatawa. Extracts were investigated for their phytochemical, antibacterial and antioxidant properties. Raju foundation, bhimavaram, andhra pradesh, india. The percentage of unsaturated fatty acid methyl esters were 52.
Euphorbia hirta is often used traditionally for female disorders, respiratory ailments cough, coryza, bronchitis, and asthma, worm infestations. Euphorbia hirta, locomotor, anticonvulsant, nootropic, anxiolytic activity. Evaluation of antimicrobial activity of euphorbia hirta and calotropis procera against mdr pathogens 1amit pandey and2nehaverma mrd life sciences pvt ltd, lucknow, 226010 abstract. A dense stand, an early colonizer of bare ground, growing beside a road. Hence the concentration of the plant extract plays a major role in determining the immnomodulatory activity. Euphorbiaceae and isolation of its bioactive constituents by shanmugapriya perumal thesis submitted in fulfilment of the requirements. Euphorbia hirta is a very popular herb amongst practitioners of traditional herbal medicine for its hypotensive, tonic, antipyretic, antiinflammatory, hypoglycemic and sedative activities. Euphorbia hirta medicinal uses for dengue treatment euphorbia hirta is one of the most important herb in ayurvedic medicine system. Antioxidant activity and phytochemical screening of the. Pretorius e uphorbiahirta isaplantusedintraditional medicine for a variety of diseases, such as cough, asthma, colic dysentery and genitourinary infection. Euphorbia hirta commonly known as tawatawa is a plant used in folklore medicine in the philippines for the treatment of dengue. Biosynthesis of silver nanoparticles using euphorbia hirta.
Euphorbia hirta is widely used as traditional medicine. Phytochemical study and screening for antimicrobial. Leaves of euphorbia hirta used in traditional medicine for the treatment of boils, wounds and control of diarrhoea and dysentery was extracted by maceration in ethanol. Antimicrobial and wound healing activities of local euphorbia. Pharmacological potential of asthma weed euphorbia hirta. India is known worldwide for its ayurvedic treatment. It is a hairy herb that grows in open grasslands, roadsides and pathways. India has tremendous wealth of aromatic and medicinal plants.
Dry fruits of caesalpinia pulcherrima leguminosae and aerial parts of euphorbia hirta euphorbiaceae and flowers asystasia gangeticum acanthaceae were collected in august 2002 from the medicinal plant garden of padmabhushan dr. Ethnobotanical information of some traditionally used indian medicinal plant species selected for antibacterial activity. Antidiabetic and free radicals scavenging potential of euphorbia hirta flower extract s. Krishnau, head, department of biology, tifr, and mumbai for analysis of samples. The leaves of various extracts of euphorbia hirta possessed lots of phytochemical constituents and have a potent in vitro antioxidant activity. Review of the phytochemical and pharmacological activities of.
Plant species family common name part used therapeutic use abrus precatoriusl. Antibacterial activity of euphorbia hirta extracts. Herbal medicine is the oldest form of medicine known to mankind. Pdf on aug 1, 2019, reena gupta and others published investigation of antimicrobial activity of euphorbia hirta leaves. Pharmacology and therapeutic potential of euphorbia hirta syn. The antibacterial and antifungal effect of euphorbia hirta was evaluated against a panel of bacteria escherichia coli, psueudomonas aeruginosa, klebsiella. Learn what are its health benefits and how you can use this to treat different diseases like dengue and stomach infection. Introduction insomnia is the inability to fall asleep. The present study was aimed at evaluating the antimicrobial and cytotoxic activities of various extracts of euphorbia hirta. The 2 deoxyribose gets oxidized and degraded to melandialdehyde in. Antidiabetic activity antioxoidnat activity phytochemical analysis euphorbia hirta strychnox nuxvomica.
Euphorbia hirta is often used traditionally for female disorders, respiratory ailments cough, coryza, bronchitis, and asthma, worm infestations in children, dysentery, jaundice, pimples, gonorrhea, digestive problems, and tumors. The present study was intended to evaluate the antifungal potential of euphorbia hirta l. Euphorbia hirta grows in human disturbed areas including roadsides, fields and yards. Euphorbia hirta, ethanolic extract, agar diffusion, inhibition, antibacterial. Euphorbia hirta is a host to many fungal pathogens and may as such act as a reservoir of pathogenic fungi, which can infect nearby susceptible crops. Asthma,euphorbia hirta and its antiinflammatory properties o. The obtained results are statistically significant atp euphorbia hirta has immunostimulant activity by stimulating both specific and nonspecific immunity at higher concentrations. Euphorbia hirta is an important plant for medicinal herb.
Invitro antimicrobial activities of euphorbia hirta against. Euphorbia hirta sometimes called asthmaplant is a pantropical weed, possibly native to india. These results suggest that euphorbia hirta have strong antioxidant potential. Research article antiradical and cytotoxic activities of varying polarity extracts of the aerial part of euphorbia hirta l. Phytto occ hheemmiiccaall cppotteennttii aall ooff. Sedative activity of ethanolic and aqueous extracts of. Asthma,euphorbia hirta and its antiinflammatory properties. Euphorbia hirta occurs throughout the island groupings of the bahamian archipelago, florida, the entire caribbean region and tropical and subtropical regions around the world. Research article antiradical and cytotoxic activities of.
Shanmugapriyaperumal, 1 roziahanimmahmud, 1 suthagarpillaipiaru, 1 weicailee, 1 andsurashramanathan 2 school of pharmaceutical sciences, univers itisainsmalaysia,penang,malaysia. Kumar institute of pharmaceutical sciences, kurukshetra university, kurukshetra6 119, india kumar, et al antidiabetic and antioxidant potentials of euphorbia hirta. The antimicrobial analysis of the leaf extract of euphorbia hirta inhibited the. Phytochemical study and screening for antimicrobial activity.
Comparative nutritional value and antimicrobial activities between. The result from this study thus showed that ethanol extracts of euphorbia hirta have potentially deleterious. Review of the phytochemical and pharmacological activities. Euphorbia hirta belong to genus euphorbia and family euphorbiaceae 12. The antidiarrhoeal activity of a lyophilized decoction of the whole plant was investigated in mice. Quercitrin, a flavonoid glycoside isolated from euphorbia hirta, showed anti diarrhoeal activity, at doses of 50.
Antifungal activity were detected only with the euphorbia hirta aqueous leaves extracts against candida tropicalis with mean inhibition zones of 8. In the philippines euphorbia hirta tea is widely taken to prevent and cure dengue fever. Pdf deadly diseases of this century were mainly caused by bacterial and fungal infections. Euphorbia hirta plant displayed an excellent antibacterial activity against k. In vitro antimicrobial activity and phytochemical analysis of. Euphorbia hirta medicinal uses for dengue treatment bimbima. Neuropharmacological activity of euphorbia hirta and its. This study aims to phytochemical and antimicrobial study of euphorbia hirta euphorbiaceae. It is a prevalent and potentially serious condition that affects the wellbeing of individuals. Alcoholic extract of euphorbia hirta whole plant has significant in vitro lipid peroxidation and scavenging activity among other polar extracts 12. Euphorbia hirta its showing very good antioxidant activity. Biological there are very few records of natural enemies attacking e. This plant, belonging to the family euphorbiaceae, is also known as the australian asthma herb or.
Moreover it is also used in different systems of medicine in the treatment of diarrhoea, bronchitis, skin diseases, fever, analgesic, gastrointestinal disorders. Pdf antimicrobial activity of fresh latex, juice and extract of. The ethanolic extract exhibited the strongest antimicrobial activity against salmonella typhi with mic value of 0. Antibacterial, antioxidant activity and phytochemical.
The aim of the current study was to investigate antibacterial activity of the ethanol and petroleum ether extracts of euphorbia hirta l against clinically important bacterial sp. Leon levy native plant preserve plant listings euphorbia. Pdf antibacterial activity of euphorbia hirta extracts researchgate. The aqueous extracts of the leaves were then tested for its wound healing properties on surgically incised mice. The oldest remedies known to mankind are herbal medicines. Euphorbia hirta is an annual hairy herb with many branches from the base to top, spreading upto 50 cm in height, reddish or purplish in color.
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